1 | // $Id: alignment_test.cc 792 2007-03-11 00:14:24Z jari $ |
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2 | |
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3 | /* |
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4 | Copyright (C) The authors contributing to this file. |
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5 | |
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6 | This file is part of the yat library, http://lev.thep.lu.se/trac/yat |
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7 | |
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8 | The yat library is free software; you can redistribute it and/or |
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9 | modify it under the terms of the GNU General Public License as |
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10 | published by the Free Software Foundation; either version 2 of the |
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11 | License, or (at your option) any later version. |
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12 | |
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13 | The yat library is distributed in the hope that it will be useful, |
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14 | but WITHOUT ANY WARRANTY; without even the implied warranty of |
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15 | MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU |
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16 | General Public License for more details. |
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17 | |
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18 | You should have received a copy of the GNU General Public License |
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19 | along with this program; if not, write to the Free Software |
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20 | Foundation, Inc., 59 Temple Place - Suite 330, Boston, MA |
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21 | 02111-1307, USA. |
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22 | */ |
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23 | |
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24 | #include "yat/utility/Alignment.h" |
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25 | |
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26 | #include "yat/utility/matrix.h" |
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27 | |
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28 | #include <gsl/gsl_cdf.h> |
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29 | |
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30 | #include <cassert> |
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31 | #include <cmath> |
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32 | #include <fstream> |
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33 | #include <iostream> |
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34 | #include <sstream> |
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35 | #include <string> |
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36 | #include <vector> |
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37 | |
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38 | using namespace theplu::yat; |
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39 | |
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40 | void read_vector(std::vector<double>& v,std::string& str) |
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41 | { |
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42 | std::istringstream s(str); |
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43 | while (!s.eof()) { |
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44 | double d; |
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45 | s >> d; |
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46 | if (!s.fail()) |
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47 | v.push_back(d); |
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48 | } |
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49 | } |
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50 | |
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51 | std::istream& operator>>(std::istream& s, |
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52 | std::vector<std::vector<double> >& m) |
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53 | { |
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54 | while (!s.eof()) { |
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55 | std::string row; |
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56 | char ch; |
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57 | while (((ch=s.get())!='\n') && s.good()) |
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58 | row+=ch; |
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59 | if (row.size() || s.good()) { // if stream good, read an empty peak set |
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60 | std::vector<double> v; |
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61 | read_vector(v,row); |
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62 | m.push_back(v); |
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63 | } |
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64 | } |
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65 | return s; |
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66 | } |
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67 | |
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68 | double match(const double x, const double y, const double s) |
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69 | { |
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70 | return 2*gsl_cdf_gaussian_Q(fabs(x-y),sqrt(2)*s); |
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71 | } |
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72 | |
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73 | |
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74 | double score(const std::vector<double>& l1, |
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75 | const std::vector<double>& l2, |
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76 | const double sigma, |
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77 | theplu::yat::utility::matrix& dot_matrix, |
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78 | std::vector<std::pair<size_t,size_t> >& path) |
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79 | { |
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80 | dot_matrix.clone(theplu::yat::utility::matrix(l1.size(),l2.size())); |
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81 | for (size_t i=0; i<l1.size(); i++) |
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82 | for (size_t j=0; j<l2.size(); j++) { |
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83 | assert(i<dot_matrix.rows()); |
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84 | assert(j<dot_matrix.columns()); |
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85 | dot_matrix(i,j)=match(l1[i],l2[j],sigma); |
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86 | } |
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87 | return theplu::yat::utility::NeedlemanWunsch(dot_matrix,path,0); |
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88 | } |
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89 | |
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90 | |
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91 | int main() |
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92 | { |
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93 | bool ok=true; |
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94 | |
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95 | std::ifstream s(std::string("data/isoform.peaks").c_str()); |
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96 | std::vector<std::vector<double> > peaksets; |
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97 | s >> peaksets; |
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98 | |
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99 | for (size_t i=0; i<peaksets.size()-1; i++) |
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100 | for (size_t j=i+1; j<peaksets.size(); j++) { |
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101 | utility::matrix dot_m; |
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102 | std::vector<std::pair<size_t,size_t> > path; |
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103 | score(peaksets[i], peaksets[j], 1.0, dot_m, path); |
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104 | } |
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105 | |
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106 | |
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107 | if (ok) { |
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108 | return 0; |
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109 | } |
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110 | return -1; |
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111 | |
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112 | } |
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